High Evidence Level Drugs
Candidates with strong clinical trial evidence for priority evaluation
Evidence Standards
| Level | Definition | Clinical Significance |
|---|---|---|
| L1 | Multiple Phase 3 RCTs / Systematic Reviews | Strong support, consider clinical use |
| L2 | Single RCT or multiple Phase 2 trials | Moderate support, design validation trial |
Drug List
L1 Level (86 drugs)
| Drug Name | Indications | Link |
|---|---|---|
| Abacavir | 10 | View Report |
| Afamelanotide | 10 | View Report |
| Afatinib | 10 | View Report |
| Agomelatine | 10 | View Report |
| Alendronic Acid | 10 | View Report |
| Alirocumab | 10 | View Report |
| Apalutamide | 10 | View Report |
| Aripiprazole | 10 | View Report |
| Asenapine | 10 | View Report |
| Atazanavir | 10 | View Report |
| Atazanavir (As Sulfate) | 50 | View Report |
| Azathioprine | 10 | View Report |
| Bazedoxifene | 10 | View Report |
| Bevacizumab | 10 | View Report |
| Bosutinib | 10 | View Report |
| Bupropion | 10 | View Report |
| Cangrelor | 10 | View Report |
| Caspofungin | 10 | View Report |
| Cilastatin | 10 | View Report |
| Clofarabine | 10 | View Report |
| Cobicistat | 10 | View Report |
| Dalbavancin | 10 | View Report |
| Darunavir | 10 | View Report |
| Desloratadine | 10 | View Report |
| Deutetrabenazine | 10 | View Report |
| Dexmedetomidine | 10 | View Report |
| Docetaxel | 10 | View Report |
| Doxorubicin | 10 | View Report |
| Dronedarone | 10 | View Report |
| Efmoroctocog Alfa | 50 | View Report |
| Emicizumab | 10 | View Report |
| Epinephrine | 10 | View Report |
| Ezetimibe | 10 | View Report |
| Faricimab | 10 | View Report |
| Fluticasone Furoate | 52 | View Report |
| Fluticasone Propionate | 10 | View Report |
| Gimeracil | 10 | View Report |
| Guanfacine | 10 | View Report |
| Guselkumab | 10 | View Report |
| Hydrocortisone | 10 | View Report |
| Ibrutinib | 10 | View Report |
| Iloprost | 10 | View Report |
| Imiquimod | 10 | View Report |
| Infliximab | 10 | View Report |
| Insulin Aspart | 10 | View Report |
| Insulin Degludec | 10 | View Report |
| Insulin Detemir | 10 | View Report |
| Insulin Glulisine | 10 | View Report |
| Ketorolac | 10 | View Report |
| Lamivudine | 10 | View Report |
| Lanadelumab | 10 | View Report |
| Lebrikizumab | 10 | View Report |
| Lenalidomide | 10 | View Report |
| Levofloxacin | 10 | View Report |
| Liraglutide | 10 | View Report |
| Lomitapide | 10 | View Report |
| Loxapine | 10 | View Report |
| Lurasidone | 10 | View Report |
| Macitentan | 10 | View Report |
| Memantine | 10 | View Report |
| Nepafenac | 10 | View Report |
| Olaparib | 10 | View Report |
| Oritavancin | 10 | View Report |
| Oteracil | 10 | View Report |
| Paclitaxel | 10 | View Report |
| Pantoprazole | 10 | View Report |
| Pegaspargase | 10 | View Report |
| Peginterferon Alfa-2A | 10 | View Report |
| Ranibizumab | 10 | View Report |
| Riociguat | 10 | View Report |
| Risperidone | 10 | View Report |
| Rituximab | 10 | View Report |
| Romiplostim | 10 | View Report |
| Simvastatin | 10 | View Report |
| Solriamfetol | 10 | View Report |
| Tacrolimus | 10 | View Report |
| Tasimelteon | 10 | View Report |
| Tazobactam | 10 | View Report |
| Tegafur | 10 | View Report |
| Temozolomide | 10 | View Report |
| Tenofovir Disoproxil | 50 | View Report |
| Teriflunomide | 10 | View Report |
| Tolvaptan | 10 | View Report |
| Trastuzumab | 10 | View Report |
| Turoctocog Alfa Pegol | 50 | View Report |
| Vilanterol | 10 | View Report |
L2 Level (76 drugs)
| Drug Name | Indications | Link |
|---|---|---|
| Acalabrutinib | 10 | View Report |
| Alemtuzumab | 10 | View Report |
| Amlodipine | 10 | View Report |
| Apremilast | 10 | View Report |
| Arsenic Trioxide | 10 | View Report |
| Atezolizumab | 10 | View Report |
| Azacitidine | 10 | View Report |
| Aztreonam | 10 | View Report |
| Basiliximab | 10 | View Report |
| Benralizumab | 10 | View Report |
| Bimatoprost | 10 | View Report |
| Brentuximab Vedotin | 10 | View Report |
| Busulfan | 10 | View Report |
| Cabazitaxel | 10 | View Report |
| Cannabidiol | 10 | View Report |
| Carmustine | 10 | View Report |
| Dasatinib | 10 | View Report |
| Dexamethasone | 10 | View Report |
| Dimethyl Fumarate | 10 | View Report |
| Elvitegravir | 10 | View Report |
| Encorafenib | 10 | View Report |
| Enfortumab Vedotin | 10 | View Report |
| Erenumab | 10 | View Report |
| Eribulin | 10 | View Report |
| Etelcalcetide | 10 | View Report |
| Everolimus | 10 | View Report |
| Fluticasone Furoate | 10 | View Report |
| Galcanezumab | 10 | View Report |
| Gilteritinib | 10 | View Report |
| Glasdegib | 10 | View Report |
| Guanfacine Hydrochloride | 50 | View Report |
| Imipenem | 10 | View Report |
| Inclisiran | 10 | View Report |
| Ivosidenib | 10 | View Report |
| Lasmiditan | 10 | View Report |
| Latanoprost | 10 | View Report |
| Ledipasvir | 10 | View Report |
| Leflunomide | 10 | View Report |
| Lidocaine | 10 | View Report |
| Melphalan | 10 | View Report |
| Methylphenidate | 10 | View Report |
| Methylphenidate Hydrochloride | 50 | View Report |
| Midazolam | 10 | View Report |
| Mycophenolate Mofetil | 10 | View Report |
| Nitric Oxide | 10 | View Report |
| Nivolumab | 10 | View Report |
| Ofatumumab | 10 | View Report |
| Olanzapine | 10 | View Report |
| Oxybutynin | 10 | View Report |
| Palbociclib | 10 | View Report |
| Pemetrexed | 10 | View Report |
| Phenylephrine | 10 | View Report |
| Pomalidomide | 10 | View Report |
| Prilocaine | 10 | View Report |
| Regorafenib | 10 | View Report |
| Risankizumab | 10 | View Report |
| Romosozumab | 10 | View Report |
| Ruxolitinib | 10 | View Report |
| Sevelamer | 10 | View Report |
| Sirolimus | 10 | View Report |
| Sodium Oxybate | 10 | View Report |
| Sorafenib | 10 | View Report |
| Spironolactone | 10 | View Report |
| Sunitinib | 10 | View Report |
| Talazoparib | 10 | View Report |
| Temsirolimus | 10 | View Report |
| Thalidomide | 10 | View Report |
| Thiotepa | 10 | View Report |
| Ticagrelor | 10 | View Report |
| Topotecan | 10 | View Report |
| Trabectedin | 10 | View Report |
| Trametinib | 10 | View Report |
| Urea | 10 | View Report |
| Ustekinumab | 10 | View Report |
| Vandetanib | 10 | View Report |
| Vildagliptin | 10 | View Report |