EuTxGNN

AI-powered drug repurposing predictions for European Medicines Agency approved drugs

View Predictions FHIR API

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Research Use Only: These predictions are for research purposes only and do not constitute medical advice. All candidates require clinical validation before therapeutic application.

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Key Statistics

Metric	Value
Total Predictions	32,368
Unique Drugs	638
Unique Indications	4,570
KG Predictions	718
DL Predictions	31,650

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Quick Start

For Researchers

1. Browse Drug Reports by evidence level
2. Download data from Downloads
3. Read the Methodology

For Developers

1. Access FHIR API for data integration
2. Launch SMART App for EHR integration
3. View source on GitHub

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Evidence Levels

Level	Definition	Count
L1	Multiple Phase 3 RCTs	0
L2	Single RCT / Phase 2	0
L3	Observational studies	0
L4	Preclinical / Case reports	0
L5	AI prediction only	32,368

View by Evidence Level

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Data Sources

Source	Description
EMA Medicines	Centrally authorized human medicines
TxGNN	Drug repurposing prediction model
DrugBank	Drug target and interaction data

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FHIR Integration

EuTxGNN provides FHIR R4 compliant resources:

Resource	Endpoint
CapabilityStatement	/fhir/metadata
MedicationKnowledge	/fhir/MedicationKnowledge/{id}
ClinicalUseDefinition	/fhir/ClinicalUseDefinition/{id}

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Citation

@article{huang2023txgnn,
  title={A foundation model for clinician-centered drug repurposing},
  author={Huang, Kexin and others},
  journal={Nature Medicine},
  year={2023},
  doi={10.1038/s41591-023-02233-x}
}

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Disclaimer

This project is for research purposes only. The predictions:

• Are not validated through clinical trials
• Should not be used for clinical decision-making
• Require professional medical evaluation before application
• Are provided “as is” without warranty

For medical advice, consult a qualified healthcare professional.